C349 smallpox
After finally escaping Pirate Island and returning to the mainland, Bai Xian did not expect himself to suddenly have smallpox. Just as he was about to explain that he had been vaccinated when he was young, he realised that he was only a soul when he teleported to this world, and his body actually grew up.
There was no vaccine in the ancient times, nor was there a medicine that was developed well