C312 The World Is Filled with Grief
If that's the case, it's possible.
Uchiha Madara felt that he had obtained Senju Hashirama's strength, and only awakened the Rinnegan when he was dying of old age.
However, it was also at this moment that Kuro Zetsu appeared.
In the thousand years after the The sage of the six path, the first person to synthesize the Rinnegan had appeared